Insufficient DNA methylation affects healthy aging and promotes age-related health problems
نویسندگان
چکیده
منابع مشابه
DNA methylation and healthy human aging
The process of aging results in a host of changes at the cellular and molecular levels, which include senescence, telomere shortening, and changes in gene expression. Epigenetic patterns also change over the lifespan, suggesting that epigenetic changes may constitute an important component of the aging process. The epigenetic mark that has been most highly studied is DNA methylation, the presen...
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ژورنال
عنوان ژورنال: Clinical Epigenetics
سال: 2011
ISSN: 1868-7075,1868-7083
DOI: 10.1007/s13148-011-0042-6